Materials Discovery Research Laboratory · TU/e
SELF-DRIVING LABS AI-GUIDED DISCOVERY CLOSED-LOOP MULTIMODAL CHARACTERISATION ELECTRON MICROSCOPY X-RAY SPECTROSCOPY FAIR DATA NATIONAL CONSORTIUM OPEN INFRASTRUCTURE SOVEREIGNTY NWO LSRI 2027

DiscoveryLabNL

Autonomous Closed-Loop Experimentation for Materials Discovery

Proposed for NWO Large-Scale Research Infrastructure · ICMS · TU/e

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The Challenge

Artificial intelligence and high-throughput laboratory automation have the potential to fundamentally transform materials and molecular research, accelerating the optimisation of desired properties, uncovering unique parameter sets, and enabling the design of materials with unprecedented features.

This potential is widely recognised across the broader materials community, yet has also produced fragmentation: parallel, disconnected efforts that fall short of the systemic integration needed to realise AI's full scientific impact.

DiscoveryLabNL is TU/e's answer: a coherent, shared infrastructure bringing together Self-Driving Laboratories, advanced multimodal characterisation, and an AI Core facility into a unified discovery platform.

TU/e's ICMS has built nationally recognised SDL foundations through the NWO Gravitation Programme Interactive Polymer Materials (IPM) and the National Growth Fund programme Big Chemistry, establishing a proven platform for this next step.

Three Pillars

Self-Driving Laboratories

Robotic synthesis and processing platforms, automated sample handling, in-line sensing and feedback systems. AI-guided closed-loop experimentation across a hub-and-spoke network of SDL nodes.

Origin: Big Chemistry (National Growth Fund) and IPM (NWO Gravitation) platforms at ICMS. Hub-and-spoke architecture allows distributed SDL nodes across campus and national partners.

Advanced Characterisation

Optical, electron and X-ray microscopy combined with spectroscopic techniques. Serves as the continuous, real-time verification and integration layer of the autonomous discovery loop.

Connects to NEMI (national electron microscopy) and XNL (X-ray Netherlands). Key verification and integration layer ensuring experimental results feed back into the AI-driven discovery loop.

AI Core Facility

FAIR data backbone, curated model catalogue, dedicated AI science team. Federated design serving the full consortium and national partners.

Aligned with SURF and Netherlands eScience Center standards. EOSC service candidate. Serves as the digital backbone connecting all SDL nodes and characterisation facilities.

Campus Consortium

Four partner institutes cover the full spectrum of materials research as equal governance partners. DIFFER is an NWO institute; ICMS, EIRES, and Casimir are TU/e institutes.

ICMS

Institute for Complex Molecular Systems. Soft Matter, Supramolecular Chemistry, Synthetic Biology.

EIRES

Eindhoven Institute for Renewable Energy Systems. Energy Materials, Electrochemistry, Battery Technology.

DIFFER

Dutch Institute for Fundamental Energy Research (NWO). Plasma Physics, Fusion Materials, Energy Conversion.

Casimir

Casimir Research Institute. Semiconductors, Photonics, Quantum Technology.

Positioning

Within TU/e

Available for materials research across all TU/e departments, serving as foundational infrastructure for the 'Intelligent Materials Labs' 10-year vision of the TU/e Flagship: Advanced Materials.

Across the Netherlands

Open-access platform serving the wider Dutch materials research community, supporting national research sovereignty and EU materials autonomy objectives. National consortium formation underway with leading universities and NWO research institutes, as required for LSRI national infrastructure designation.

TU/e Investment

€20-30M indicative range. Subject to TU/e EB negotiation. Target cycle: NWO LSRI 2027.

Roadmap

Indicative timeline, subject to revision

Mar 2026
Initiation & Alignment
Project charter, governance structure, Executive Board endorsement
We are here
Q2–Q3 2026
Concept & Architecture
Three-pillar technical design, national consortium formation, partnership agreements
Q3 2026
Stakeholder Validation
Institute and Flagship alignment, co-funding commitments, advisory board formation
Q4 2026
Pilot & Investment
Pilot project portfolio, phased investment logic, LSRI proposal drafting
2027
NWO LSRI Submission
Full proposal to NWO, external review readiness

Team

Core Leadership

Jan van Hest Scientific Lead, ICMS / TU/e
Yuyang Wang Initiative Lead, ICMS / TU/e
Monique Bruining Initiative Co-lead, ICMS / TU/e

Flagship Contributing Partners

Nicholas Tito Contributing Partner, TU/e Flagship
Marc Geers Flagship Lead, ICMS / TU/e
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Stakeholder Momentum

Strong institutional anchors, real momentum, active engagement. The concentric rings below show stakeholder commitment levels across the national materials discovery ecosystem. Click any name for details.

Jan van Hest Yuyang Wang Monique Bruining Nicholas Tito Marc Geers Koen Janssen Tom de Greef Ilja Voets Peter Zijlstra Lorenzo Albertazzi Renée Westenbrink Mark Boneschanscher Mark van Assem Süleyman Er Shuxia Tao Erik Bakkers Luc Brunsveld Timothy Noël Francesco Staps Richard van de Sanden Carlijn Bouten Jaap den Toonder Heiner Friedrich Monica Morales-Masis
Core Team
Committed
In Dialogue
Planned

Status
Role
Organisation
Notes
Pinch to zoom · tap a name for details

3 core · 7 committed · 7 in dialogue · 7 planned

Contact and Next Steps

Initiative Lead: Yuyang Wang ✉ email

Scientific Lead: Jan van Hest ✉ email

Organisation: ICMS · TU/e

Key Milestones

Indicative, subject to revision

  • April 2026: Executive Board alignment meeting
  • Q2-Q3 2026: National consortium formation with leading universities and NWO institutes
  • Q4 2026: Phased investment logic and LSRI proposal preparation
  • 2027: NWO LSRI submission

This briefing is shared with TU/e internal stakeholders. We welcome colleagues who wish to contribute to shaping DiscoveryLabNL, whether scientifically or organisationally. Members of the LSRI Group Materials are particularly encouraged to reach out so we can explore alignment and collaboration opportunities together.